Moxidectin + Praziquantel side effects in horses
372 reports sent to the FDA between 2003 and 2026 involve Moxidectin + Praziquantel in horses. The most reported problems were loss of appetite, colic, lethargy. 23% were marked serious.
About this medicine
Moxidectin prevents heartworm disease (monthly topical, or a 6- or 12-month injection for dogs). Praziquantel treats tapeworms.
Some herding breeds (for example Collies) carry the MDR1 gene variant and can be more sensitive to this drug class at high doses.
Most reported side effects
Share = percentage of this medicine's reports that mention the problem. One report can list several problems.
Reports that it didn't work
Some reports are about the medicine not working (for example a horse still getting fleas or heartworm), not about a side effect.
How soon problems started
Time from the first dose to the first sign, where both dates were reported (236 reports).
How the animals did
Breeds named most often
Popular breeds appear more often because there are more of them.
- Quarter Horse 106 reports
- Horse 52 reports
- Thoroughbred 38 reports
- Paint 26 reports
- Arab 13 reports
- Miniature 12 reports
- Tennessee Walking Horse 9 reports
- Warmblood 9 reports
- Morgan 7 reports
- Mustang 6 reports