Ivermectin + Praziquantel side effects in horses
2,648 reports sent to the FDA between 2003 and 2026 involve Ivermectin + Praziquantel in horses. The most reported problems were swelling, drooling, application site reaction. 22% were marked serious.
About this medicine
Ivermectin prevents heartworm disease (monthly). Praziquantel treats tapeworms.
Some herding breeds (for example Collies) carry the MDR1 gene variant and can be more sensitive to this drug class at high doses.
Most reported side effects
Share = percentage of this medicine's reports that mention the problem. One report can list several problems.
Reports that it didn't work
Some reports are about the medicine not working (for example a horse still getting fleas or heartworm), not about a side effect.
How soon problems started
Time from the first dose to the first sign, where both dates were reported (786 reports).
How the animals did
Breeds named most often
Popular breeds appear more often because there are more of them.
- Horse 631 reports
- Quarter Horse 513 reports
- Thoroughbred 359 reports
- Arab 176 reports
- Paint 127 reports
- Horse (other) 101 reports
- Appaloosa 56 reports
- Tennessee Walking Horse 55 reports
- Dutch Warmblood 45 reports
- Hanovarian 40 reports