Allergic reaction after Ivermectin + Praziquantel in horses
The FDA has received 312 reports of allergic reaction in horses after Ivermectin + Praziquantel. That is 12% of all reports for this medicine, compared with 7.5% across reports for all horse medicines, so it is reported unusually often with this medicine.
312Reports
40%Marked serious
25%Recovered
1.3%Died or euthanised
Same dayTypical onset
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How soon it started
How the animals did
Problems reported at the same time
Age of the animals
About this medicine
Ivermectin prevents heartworm disease (monthly). Praziquantel treats tapeworms.
Some herding breeds (for example Collies) carry the MDR1 gene variant and can be more sensitive to this drug class at high doses.
Questions owners ask
- Can Ivermectin + Praziquantel cause allergic reaction in horses?
- 312 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
- How soon after a dose was it reported?
- In half of the reports with dates, it started within the same day of the first dose.
- What should I do?
- Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).
Allergic reaction with similar medicines
- Allergic reaction after Moxidectin (ProHeart 6) 62 reports · 4.5% of its reports
- Allergic reaction after Ivermectin (Heartgard) 35 reports · 5.1% of its reports
- Allergic reaction after Moxidectin + Praziquantel 27 reports · 7.3% of its reports
All reported side effects of Ivermectin + Praziquantel in horses · Medicines most reported with allergic reaction