Abdominal pain after Moxidectin + Praziquantel in horses
The FDA has received 27 reports of abdominal pain in horses after Moxidectin + Praziquantel. That is 7.3% of all reports for this medicine, compared with 5.7% across reports for all horse medicines.
27Reports
0.0%Marked serious
0.0%Recovered
15%Died or euthanised
–Typical onset
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How the animals did
Problems reported at the same time
Age of the animals
About this medicine
Moxidectin prevents heartworm disease (monthly topical, or a 6- or 12-month injection for dogs). Praziquantel treats tapeworms.
Some herding breeds (for example Collies) carry the MDR1 gene variant and can be more sensitive to this drug class at high doses.
Questions owners ask
- Can Moxidectin + Praziquantel cause abdominal pain in horses?
- 27 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
- What should I do?
- Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).
Abdominal pain with similar medicines
- Abdominal pain after Ivermectin + Praziquantel 198 reports · 7.5% of its reports
- Abdominal pain after Moxidectin (ProHeart 6) 180 reports · 13% of its reports
- Abdominal pain after Ivermectin (Heartgard) 107 reports · 16% of its reports
All reported side effects of Moxidectin + Praziquantel in horses · Medicines most reported with abdominal pain