Leucocytosis after Vitamin K in dogs

The FDA has received 23 reports of leucocytosis in dogs after Vitamin K. That is 17% of all reports for this medicine, compared with 1.0% across reports for all dog medicines, so it is reported unusually often with this medicine.

23Reports
91%Marked serious
8.7%Recovered
61%Died or euthanised
9 daysTypical onset
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How soon it started

Same day
1 5.0%
1–2 days
4 20%
3–7 days
5 25%
1–4 weeks
7 35%
Over a month
3 15%

How the animals did

Recovered
2 8.7%
Still unwell when reported
7 30%
Died
4 17%
Euthanised
10 43%

Problems reported at the same time

16 70%
14 61%
12 52%
Neutrophilia
10 43%

Age of the animals

Under 1 year
1
1–3 years
4
4–7 years
8
8–11 years
7
12+ years
3

About this medicine

Type: medicine.

Questions owners ask

Can Vitamin K cause leucocytosis in dogs?
23 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 9 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Leucocytosis with similar medicines

All reported side effects of Vitamin K in dogs · Medicines most reported with leucocytosis