Loss of appetite after Vincristine in dogs

The FDA has received 29 reports of loss of appetite in dogs after Vincristine. That is 55% of all reports for this medicine, compared with 8.4% across reports for all dog medicines, so it is reported unusually often with this medicine.

29Reports
100%Marked serious
0.0%Recovered
59%Died or euthanised
16 daysTypical onset
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How soon it started

Same day
3 14%
1–2 days
1 4.8%
3–7 days
3 14%
1–4 weeks
9 43%
Over a month
5 24%

How the animals did

Still unwell when reported
10 34%
Died
6 21%
Euthanised
11 38%
Not known
2 6.9%

Problems reported at the same time

18 62%
17 59%
16 55%
Liver problems
13 45%
Leucocytosis
12 41%
Diarrhea
8 28%
Neutrophilia
6 21%

Age of the animals

Under 1 year
0
1–3 years
3
4–7 years
16
8–11 years
10
12+ years
0

About this medicine

Type: medicine.

Questions owners ask

Can Vincristine cause loss of appetite in dogs?
29 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 16 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Loss of appetite with similar medicines

All reported side effects of Vincristine in dogs · Medicines most reported with loss of appetite