Death after Vincristine in dogs

25 reports to the FDA describe death in dogs given Vincristine. That is 47% of all reports for this medicine, compared with 5.2% across reports for all dog medicines, so it is reported unusually often with this medicine.

25Reports
96%Marked serious
0.0%Recovered
100%Died or euthanised
16 daysTypical onset
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How soon it started

Same day
3 17%
1–2 days
1 5.6%
3–7 days
2 11%
1–4 weeks
6 33%
Over a month
6 33%

How the animals did

Died
10 40%
Euthanised
15 60%

Problems reported at the same time

13 52%
Liver problems
12 48%
Leucocytosis
11 44%
10 40%
Diarrhea
8 32%
Neutrophilia
8 32%

Age of the animals

Under 1 year
0
1–3 years
1
4–7 years
8
8–11 years
14
12+ years
2

About this medicine

Type: medicine.

Questions owners ask

Can Vincristine cause death in dogs?
25 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 16 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Death with similar medicines

All reported side effects of Vincristine in dogs · Medicines most reported with death