Flaking skin after Trilostane (Vetoryl) in dogs

52 reports to the FDA describe flaking skin in dogs given Trilostane. That is 0.4% of all reports for this medicine, compared with 0.1% across reports for all dog medicines, so it is reported unusually often with this medicine.

52Reports

62%Marked serious

3.8%Recovered

5.8%Died or euthanised

35 daysTypical onset

How soon it started

Same day

0 0.0%

1–2 days

2 4.4%

3–7 days

1 2.2%

1–4 weeks

15 33%

Over a month

27 60%

How the animals did

Recovered

2 3.8%

Still unwell when reported

13 25%

Died

1 1.9%

Euthanised

2 3.8%

Not known

34 65%

Problems reported at the same time

20 38%

14 27%

12 23%

10 19%

10 19%

Didn't work as expected

10 19%

Diarrhea

8 15%

Bacterial skin infection

7 13%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Trilostane treats Cushing's disease (an overactive adrenal gland).

Products with this ingredient include Vetoryl. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Trilostane cause flaking skin in dogs?: 52 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 35 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Flaking skin with similar medicines

Flaking skin after Levothyroxine 30 reports · 1.0% of its reports

All reported side effects of Trilostane in dogs · Medicines most reported with flaking skin