Blood in urine after Trilostane (Vetoryl) in dogs

109 reports to the FDA describe blood in urine in dogs given Trilostane. That is 0.9% of all reports for this medicine, compared with 0.2% across reports for all dog medicines, so it is reported unusually often with this medicine.

109Reports

72%Marked serious

2.8%Recovered

21%Died or euthanised

60 daysTypical onset

How soon it started

Same day

3 3.6%

1–2 days

4 4.8%

3–7 days

4 4.8%

1–4 weeks

18 22%

Over a month

54 65%

How the animals did

Recovered

3 2.8%

Still unwell when reported

20 18%

Died

5 4.6%

Euthanised

18 17%

Not known

63 58%

Problems reported at the same time

Urinary tract infection

42 39%

Liver problems

41 38%

Proteinuria

34 31%

Loss of appetite

30 28%

Decreased urine concentration

26 24%

Death

23 21%

Kidney problems

22 20%

Lethargy

21 19%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Trilostane treats Cushing's disease (an overactive adrenal gland).

Products with this ingredient include Vetoryl. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Trilostane cause blood in urine in dogs?: 109 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 60 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Blood in urine with similar medicines

Blood in urine after Insulin 24 reports · 0.3% of its reports

All reported side effects of Trilostane in dogs · Medicines most reported with blood in urine