Didn't work as expected after Trazodone in dogs

290 reports to the FDA describe didn't work as expected in dogs given Trazodone. That is 11% of all reports for this medicine, compared with 13% across reports for all dog medicines.

290Reports

42%Marked serious

16%Recovered

8.3%Died or euthanised

27 daysTypical onset

How soon it started

Same day

47 22%

1–2 days

13 6.1%

3–7 days

14 6.6%

1–4 weeks

40 19%

Over a month

99 46%

How the animals did

Recovered

44 15%

Recovered with lasting effects

2 0.7%

Still unwell when reported

93 32%

Died

6 2.1%

Euthanised

18 6.2%

Not known

127 44%

Problems reported at the same time

37 13%

37 13%

30 10%

24 8.3%

24 8.3%

23 7.9%

21 7.2%

Injection site reaction

17 5.9%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Trazodone reduces anxiety and stress.

Questions owners ask

Can Trazodone cause didn't work as expected in dogs?: 290 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 27 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Didn't work as expected with similar medicines

Didn't work as expected after Gabapentin 1,277 reports · 14% of its reports
Didn't work as expected after Selegiline (Anipryl) 1,228 reports · 30% of its reports
Didn't work as expected after Fluoxetine 489 reports · 19% of its reports
Didn't work as expected after Clomipramine (Clomicalm) 187 reports · 12% of its reports

All reported side effects of Trazodone in dogs · Medicines most reported with didn't work as expected