Decreased packed cell volume (pcv) after Tramadol in dogs

50 reports to the FDA describe decreased packed cell volume (pcv) in dogs given Tramadol. That is 1.3% of all reports for this medicine, compared with 0.1% across reports for all dog medicines, so it is reported unusually often with this medicine.

50Reports

72%Marked serious

14%Recovered

28%Died or euthanised

32 daysTypical onset

How soon it started

Same day

2 6.9%

1–2 days

3 10%

3–7 days

7 24%

1–4 weeks

2 6.9%

Over a month

15 52%

How the animals did

Recovered

7 14%

Still unwell when reported

24 48%

Died

1 2.0%

Euthanised

13 26%

Not known

5 10%

Problems reported at the same time

26 52%

23 46%

21 42%

21 42%

18 36%

17 34%

14 28%

13 26%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Type: medicine.

Questions owners ask

Can Tramadol cause decreased packed cell volume (pcv) in dogs?: 50 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 32 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Decreased packed cell volume (pcv) with similar medicines

Decreased packed cell volume (pcv) after Melarsomine (Immiticide) 30 reports · 0.1% of its reports
Decreased packed cell volume (pcv) after Polysulfated Glycosaminoglycan 46 reports · 0.8% of its reports
Decreased packed cell volume (pcv) after Diphenhydramine 58 reports · 1.2% of its reports
Decreased packed cell volume (pcv) after Butorphanol 25 reports · 0.6% of its reports
Decreased packed cell volume (pcv) after Cefpodoxime 34 reports · 0.8% of its reports
Decreased packed cell volume (pcv) after Desoxycorticosterone Pivalate 37 reports · 1.1% of its reports
Decreased packed cell volume (pcv) after Famotidine 53 reports · 2.0% of its reports
Decreased packed cell volume (pcv) after Chondroitin + Glucosamine 24 reports · 0.9% of its reports
Decreased packed cell volume (pcv) after Ketoconazole 21 reports · 0.9% of its reports
Decreased packed cell volume (pcv) after Sucralfate 37 reports · 3.8% of its reports

All reported side effects of Tramadol in dogs · Medicines most reported with decreased packed cell volume (pcv)