Decreased packed cell volume (pcv) after Desoxycorticosterone Pivalate in dogs

The FDA has received 37 reports of decreased packed cell volume (pcv) in dogs after Desoxycorticosterone Pivalate. That is 1.1% of all reports for this medicine, compared with 0.1% across reports for all dog medicines, so it is reported unusually often with this medicine.

37Reports

73%Marked serious

0.0%Recovered

24%Died or euthanised

14 daysTypical onset

How soon it started

Same day

2 10%

1–2 days

1 5.0%

3–7 days

5 25%

1–4 weeks

5 25%

Over a month

7 35%

How the animals did

Still unwell when reported

7 19%

Died

2 5.4%

Euthanised

7 19%

Not known

21 57%

Problems reported at the same time

Blood problems

18 49%

Lethargy

13 35%

Kidney problems

11 30%

Decreased red blood cell count

11 30%

11 30%

10 27%

9 24%

8 22%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Type: medicine.

Questions owners ask

Can Desoxycorticosterone Pivalate cause decreased packed cell volume (pcv) in dogs?: 37 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 14 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Decreased packed cell volume (pcv) with similar medicines

Decreased packed cell volume (pcv) after Melarsomine (Immiticide) 30 reports · 0.1% of its reports
Decreased packed cell volume (pcv) after Polysulfated Glycosaminoglycan 46 reports · 0.8% of its reports
Decreased packed cell volume (pcv) after Diphenhydramine 58 reports · 1.2% of its reports
Decreased packed cell volume (pcv) after Butorphanol 25 reports · 0.6% of its reports
Decreased packed cell volume (pcv) after Cefpodoxime 34 reports · 0.8% of its reports
Decreased packed cell volume (pcv) after Tramadol 50 reports · 1.3% of its reports
Decreased packed cell volume (pcv) after Famotidine 53 reports · 2.0% of its reports
Decreased packed cell volume (pcv) after Chondroitin + Glucosamine 24 reports · 0.9% of its reports
Decreased packed cell volume (pcv) after Ketoconazole 21 reports · 0.9% of its reports
Decreased packed cell volume (pcv) after Sucralfate 37 reports · 3.8% of its reports

All reported side effects of Desoxycorticosterone Pivalate in dogs · Medicines most reported with decreased packed cell volume (pcv)