Fever after Spinosad (Comfortis) in dogs
The FDA has received 412 reports of fever in dogs after Spinosad. That is 0.7% of all reports for this medicine, compared with 1.4% across reports for all dog medicines, so it is reported less often than average with this medicine.
412Reports
28%Marked serious
24%Recovered
13%Died or euthanised
1 daysTypical onset
Sponsored
How soon it started
How the animals did
Problems reported at the same time
Age of the animals
About this medicine
Spinosad kills fleas; monthly chewable.
Products with this ingredient include Comfortis. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.
Questions owners ask
- Can Spinosad cause fever in dogs?
- 412 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
- How soon after a dose was it reported?
- In half of the reports with dates, it started within 1 day of the first dose.
- What should I do?
- Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).
Fever with similar medicines
- Fever after Lufenuron + Milbemycin Oxime (Sentinel) 178 reports · 0.7% of its reports
- Fever after Imidacloprid + Moxidectin (Advantage Multi) 165 reports · 1.3% of its reports
- Fever after Nitenpyram (Capstar) 78 reports · 0.7% of its reports
- Fever after Lufenuron + Milbemycin Oxime + Praziquantel (Sentinel Spectrum) 35 reports · 0.4% of its reports
- Fever after Fipronil + S-methoprene (Frontline Plus) 44 reports · 1.5% of its reports
- Fever after Flumethrin + Imidacloprid (Seresto) 31 reports · 1.4% of its reports
- Fever after Lufenuron 41 reports · 4.0% of its reports
All reported side effects of Spinosad in dogs · Medicines most reported with fever