Fever after Flumethrin + Imidacloprid (Seresto) in dogs

31 reports to the FDA describe fever in dogs given Flumethrin + Imidacloprid. That is 1.4% of all reports for this medicine, compared with 1.4% across reports for all dog medicines.

31Reports
81%Marked serious
19%Recovered
16%Died or euthanised
57 daysTypical onset
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How soon it started

Same day
2 9.5%
1–2 days
1 4.8%
3–7 days
3 14%
1–4 weeks
4 19%
Over a month
11 52%

How the animals did

Recovered
5 16%
Recovered with lasting effects
1 3.2%
Still unwell when reported
7 23%
Died
3 9.7%
Euthanised
2 6.5%
Not known
13 42%

Problems reported at the same time

Age of the animals

Under 1 year
5
1–3 years
10
4–7 years
11
8–11 years
4
12+ years
0

About this medicine

Imidacloprid kills fleas (spot-on or collar).

Products with this combination include Seresto. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Flumethrin + Imidacloprid cause fever in dogs?
31 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 57 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Fever with similar medicines

All reported side effects of Flumethrin + Imidacloprid in dogs · Medicines most reported with fever