Spasm after Selamectin (Revolution) in dogs

26 reports to the FDA describe spasm in dogs given Selamectin. That is 0.1% of all reports for this medicine, compared with 0.1% across reports for all dog medicines.

26Reports
12%Marked serious
12%Recovered
12%Died or euthanised
–Typical onset
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How the animals did

Recovered
3 12%
Died
3 12%
Not known
20 77%

Problems reported at the same time

Age of the animals

Under 1 year
2
1–3 years
12
4–7 years
9
8–11 years
2
12+ years
0

About this medicine

Selamectin prevents heartworm and treats fleas, ear mites and some worms (spot-on).

Products with this ingredient include Revolution. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Some herding breeds (for example Collies) carry the MDR1 gene variant and can be more sensitive to this drug class at high doses.

Questions owners ask

Can Selamectin cause spasm in dogs?
26 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Spasm with similar medicines

All reported side effects of Selamectin in dogs · Medicines most reported with spasm