Unresponsive after Sarolaner (Simparica) in dogs
62 reports to the FDA describe unresponsive in dogs given Sarolaner. That is 0.4% of all reports for this medicine, compared with 0.4% across reports for all dog medicines.
62Reports
81%Marked serious
27%Recovered
24%Died or euthanised
Same dayTypical onset
Sponsored
How soon it started
How the animals did
Problems reported at the same time
Age of the animals
About this medicine
Sarolaner kills fleas, ticks and some mites; monthly.
Products with this ingredient include Simparica. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.
In 2018 the FDA alerted owners and vets that isoxazoline products have been associated with neurologic reactions such as muscle tremors, wobbliness (ataxia) and seizures, including in animals with no history of them.
Questions owners ask
- Can Sarolaner cause unresponsive in dogs?
- 62 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
- How soon after a dose was it reported?
- In half of the reports with dates, it started within the same day of the first dose.
- What should I do?
- Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).
Unresponsive with similar medicines
- Unresponsive after Fluralaner (Bravecto) 225 reports · 0.3% of its reports
- Unresponsive after Afoxolaner (NexGard) 223 reports · 0.4% of its reports
- Unresponsive after Lotilaner (Credelio) 32 reports · 0.3% of its reports
- Unresponsive after Afoxolaner + Moxidectin + Pyrantel (NexGard PLUS) 28 reports · 0.3% of its reports
All reported side effects of Sarolaner in dogs · Medicines most reported with unresponsive