Lateral recumbency after Sarolaner (Simparica) in dogs
The FDA has received 48 reports of lateral recumbency in dogs after Sarolaner. That is 0.3% of all reports for this medicine, compared with 0.3% across reports for all dog medicines.
48Reports
96%Marked serious
15%Recovered
38%Died or euthanised
1 daysTypical onset
How soon it started
How the animals did
Problems reported at the same time
Age of the animals
About this medicine
Sarolaner kills fleas, ticks and some mites; monthly.
Products with this ingredient include Simparica. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.
In 2018 the FDA alerted owners and vets that isoxazoline products have been associated with neurologic reactions such as muscle tremors, wobbliness (ataxia) and seizures, including in animals with no history of them.
Questions owners ask
- Can Sarolaner cause lateral recumbency in dogs?
- 48 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
- How soon after a dose was it reported?
- In half of the reports with dates, it started within 1 day of the first dose.
- What should I do?
- Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).
Lateral recumbency with similar medicines
- Lateral recumbency after Fluralaner (Bravecto) 288 reports · 0.4% of its reports
- Lateral recumbency after Afoxolaner (NexGard) 273 reports · 0.5% of its reports
- Lateral recumbency after Afoxolaner + Moxidectin + Pyrantel (NexGard PLUS) 37 reports · 0.4% of its reports
All reported side effects of Sarolaner in dogs · Medicines most reported with lateral recumbency
