Behaviour change after Pyrantel in dogs

103 reports to the FDA describe behaviour change in dogs given Pyrantel. That is 2.2% of all reports for this medicine, compared with 2.5% across reports for all dog medicines.

103Reports

43%Marked serious

18%Recovered

18%Died or euthanised

2 daysTypical onset

How soon it started

Same day

20 36%

1–2 days

9 16%

3–7 days

7 13%

1–4 weeks

15 27%

Over a month

5 8.9%

How the animals did

Recovered

18 17%

Recovered with lasting effects

1 1.0%

Still unwell when reported

19 18%

Died

11 11%

Euthanised

8 7.8%

Not known

46 45%

Problems reported at the same time

31 30%

29 28%

26 25%

20 19%

19 18%

17 17%

14 14%

14 14%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Pyrantel treats roundworms and hookworms.

Questions owners ask

Can Pyrantel cause behaviour change in dogs?: 103 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 2 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Behaviour change with similar medicines

Behaviour change after Pyrantel + Sarolaner (Simparica Trio) 1,082 reports · 2.0% of its reports
Behaviour change after Febantel + Praziquantel + Pyrantel (Drontal Plus) 285 reports · 4.2% of its reports
Behaviour change after Fenbendazole 213 reports · 3.6% of its reports
Behaviour change after Praziquantel + Pyrantel 147 reports · 4.0% of its reports
Behaviour change after Praziquantel 31 reports · 2.8% of its reports

All reported side effects of Pyrantel in dogs · Medicines most reported with behaviour change