Pentobarbital + Phenytoin side effects in dogs

848 reports sent to the FDA between 1995 and 2026 involve Pentobarbital + Phenytoin in dogs. The most reported problems were overdose, vocalising, breathing problems. 32% were marked serious, and where it was recorded, signs eased after stopping the medicine in 48% of cases.

848Reports
32%Marked serious
95%Only medicine involved
1.9%Recovered
86%Died or euthanised
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About this medicine

Type: medicine.

Most reported side effects

90 11%
Behaviour change
14 1.7%
Lethargy
13 1.5%
Sedation
13 1.5%
Wobbliness (ataxia)
12 1.4%
Itching
11 1.3%
Pain
10 1.2%

Share = percentage of this medicine's reports that mention the problem. One report can list several problems.

Reports that it didn't work

Some reports are about the medicine not working (for example a dog still getting fleas or heartworm), not about a side effect.

How soon problems started

Same day
269 98%
1–2 days
1 0.4%
3–7 days
1 0.4%
1–4 weeks
2 0.7%
Over a month
1 0.4%

Time from the first dose to the first sign, where both dates were reported (274 reports).

How the animals did

Recovered
16 1.9%
Died
371 44%
Euthanised
358 42%
Not known
103 12%

Breeds named most often

Popular breeds appear more often because there are more of them.

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