Vocalising after Pentobarbital + Phenytoin in dogs

87 reports to the FDA describe vocalising in dogs given Pentobarbital + Phenytoin. That is 10% of all reports for this medicine, compared with 1.2% across reports for all dog medicines, so it is reported unusually often with this medicine.

87Reports
44%Marked serious
1.1%Recovered
93%Died or euthanised
Same dayTypical onset
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How soon it started

Same day
35 95%
1–2 days
0 0.0%
3–7 days
1 2.7%
1–4 weeks
1 2.7%
Over a month
0 0.0%

How the animals did

Recovered
1 1.1%
Died
34 39%
Euthanised
47 54%
Not known
5 5.7%

Problems reported at the same time

16 18%
12 14%
Behaviour change
10 11%
Pain
7 8.0%
Muscle stiffness
6 6.9%

Age of the animals

Under 1 year
0
1–3 years
3
4–7 years
4
8–11 years
9
12+ years
29

About this medicine

Type: medicine.

Questions owners ask

Can Pentobarbital + Phenytoin cause vocalising in dogs?
87 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within the same day of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Vocalising with similar medicines

All reported side effects of Pentobarbital + Phenytoin in dogs · Medicines most reported with vocalising