Elevated cholesterol (total) after Ondansetron in dogs

25 reports to the FDA describe elevated cholesterol (total) in dogs given Ondansetron. That is 3.8% of all reports for this medicine, compared with 0.3% across reports for all dog medicines, so it is reported unusually often with this medicine.

25Reports

88%Marked serious

4.0%Recovered

64%Died or euthanised

13 daysTypical onset

How soon it started

Same day

4 18%

1–2 days

4 18%

3–7 days

1 4.5%

1–4 weeks

4 18%

Over a month

9 41%

How the animals did

Recovered

1 4.0%

Still unwell when reported

6 24%

Died

2 8.0%

Euthanised

14 56%

Not known

2 8.0%

Problems reported at the same time

23 92%

20 80%

19 76%

17 68%

16 64%

15 60%

13 52%

Abnormal ultrasound finding

12 48%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Type: medicine.

Questions owners ask

Can Ondansetron cause elevated cholesterol (total) in dogs?: 25 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 13 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Elevated cholesterol (total) with similar medicines

Elevated cholesterol (total) after Melarsomine (Immiticide) 26 reports · 0.1% of its reports
Elevated cholesterol (total) after Polysulfated Glycosaminoglycan 60 reports · 1.1% of its reports
Elevated cholesterol (total) after Diphenhydramine 23 reports · 0.5% of its reports
Elevated cholesterol (total) after Butorphanol 29 reports · 0.7% of its reports
Elevated cholesterol (total) after Cefpodoxime 26 reports · 0.6% of its reports
Elevated cholesterol (total) after Tramadol 32 reports · 0.8% of its reports
Elevated cholesterol (total) after Famotidine 33 reports · 1.2% of its reports
Elevated cholesterol (total) after Chondroitin + Glucosamine 39 reports · 1.5% of its reports
Elevated cholesterol (total) after Enalapril 22 reports · 1.3% of its reports
Elevated cholesterol (total) after Ampicillin 27 reports · 2.8% of its reports

All reported side effects of Ondansetron in dogs · Medicines most reported with elevated cholesterol (total)