Elevated cholesterol (total) after Butorphanol in dogs

The FDA has received 29 reports of elevated cholesterol (total) in dogs after Butorphanol. That is 0.7% of all reports for this medicine, compared with 0.3% across reports for all dog medicines, so it is reported unusually often with this medicine.

29Reports

66%Marked serious

21%Recovered

41%Died or euthanised

43 daysTypical onset

How soon it started

Same day

5 25%

1–2 days

0 0.0%

3–7 days

3 15%

1–4 weeks

2 10%

Over a month

10 50%

How the animals did

Recovered

5 17%

Recovered with lasting effects

1 3.4%

Still unwell when reported

7 24%

Died

4 14%

Euthanised

8 28%

Not known

4 14%

Problems reported at the same time

25 86%

17 59%

16 55%

14 48%

14 48%

12 41%

Elevated gamma-glutamyl transferase (ggt)

10 34%

Diarrhea

10 34%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Type: medicine.

Questions owners ask

Can Butorphanol cause elevated cholesterol (total) in dogs?: 29 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 43 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Elevated cholesterol (total) with similar medicines

Elevated cholesterol (total) after Melarsomine (Immiticide) 26 reports · 0.1% of its reports
Elevated cholesterol (total) after Polysulfated Glycosaminoglycan 60 reports · 1.1% of its reports
Elevated cholesterol (total) after Diphenhydramine 23 reports · 0.5% of its reports
Elevated cholesterol (total) after Cefpodoxime 26 reports · 0.6% of its reports
Elevated cholesterol (total) after Tramadol 32 reports · 0.8% of its reports
Elevated cholesterol (total) after Famotidine 33 reports · 1.2% of its reports
Elevated cholesterol (total) after Chondroitin + Glucosamine 39 reports · 1.5% of its reports
Elevated cholesterol (total) after Enalapril 22 reports · 1.3% of its reports
Elevated cholesterol (total) after Ampicillin 27 reports · 2.8% of its reports
Elevated cholesterol (total) after Ursodiol 25 reports · 3.4% of its reports

All reported side effects of Butorphanol in dogs · Medicines most reported with elevated cholesterol (total)