Dehydration after Ondansetron in dogs

70 reports to the FDA describe dehydration in dogs given Ondansetron. That is 11% of all reports for this medicine, compared with 0.7% across reports for all dog medicines, so it is reported unusually often with this medicine.

70Reports
87%Marked serious
4.3%Recovered
57%Died or euthanised
14 daysTypical onset
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How soon it started

Same day
11 19%
1–2 days
11 19%
3–7 days
6 10%
1–4 weeks
12 20%
Over a month
19 32%

How the animals did

Recovered
3 4.3%
Still unwell when reported
23 33%
Died
10 14%
Euthanised
30 43%
Not known
4 5.7%

Problems reported at the same time

Age of the animals

Under 1 year
6
1–3 years
20
4–7 years
16
8–11 years
20
12+ years
8

About this medicine

Type: medicine.

Questions owners ask

Can Ondansetron cause dehydration in dogs?
70 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 14 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Dehydration with similar medicines

All reported side effects of Ondansetron in dogs · Medicines most reported with dehydration