Dehydration after Melarsomine (Immiticide) in dogs

The FDA has received 176 reports of dehydration in dogs after Melarsomine. That is 0.8% of all reports for this medicine, compared with 0.7% across reports for all dog medicines.

176Reports

44%Marked serious

5.1%Recovered

16%Died or euthanised

6 daysTypical onset

How soon it started

Same day

14 15%

1–2 days

21 22%

3–7 days

16 17%

1–4 weeks

17 18%

Over a month

26 28%

How the animals did

Recovered

9 5.1%

Still unwell when reported

57 32%

Died

20 11%

Euthanised

8 4.5%

Not known

82 47%

Problems reported at the same time

93 53%

75 43%

74 42%

71 40%

60 34%

34 19%

31 18%

30 17%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Melarsomine treats adult heartworm infection (a series of injections given by a vet).

Products with this ingredient include Immiticide, Diroban. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Melarsomine cause dehydration in dogs?: 176 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 6 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Dehydration with similar medicines

Dehydration after Polysulfated Glycosaminoglycan 110 reports · 2.0% of its reports
Dehydration after Diphenhydramine 104 reports · 2.2% of its reports
Dehydration after Butorphanol 103 reports · 2.3% of its reports
Dehydration after Cefpodoxime 66 reports · 1.6% of its reports
Dehydration after Tramadol 140 reports · 3.7% of its reports
Dehydration after Florfenicol + Mometasone + Terbinafine 49 reports · 1.4% of its reports
Dehydration after Desoxycorticosterone Pivalate 89 reports · 2.7% of its reports
Dehydration after Propofol 48 reports · 1.6% of its reports
Dehydration after Dirlotapide 26 reports · 0.9% of its reports
Dehydration after Isoflurane 60 reports · 2.2% of its reports

All reported side effects of Melarsomine in dogs · Medicines most reported with dehydration