Swelling after Oclacitinib (Apoquel) in dogs

824 reports to the FDA describe swelling in dogs given Oclacitinib. That is 2.8% of all reports for this medicine, compared with 2.8% across reports for all dog medicines.

824Reports
52%Marked serious
21%Recovered
9.1%Died or euthanised
14 daysTypical onset
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How soon it started

Same day
180 29%
1–2 days
66 10%
3–7 days
51 8.1%
1–4 weeks
83 13%
Over a month
251 40%

How the animals did

Recovered
173 21%
Recovered with lasting effects
2 0.2%
Still unwell when reported
471 57%
Died
28 3.4%
Euthanised
47 5.7%
Not known
103 13%

Problems reported at the same time

Age of the animals

Under 1 year
17
1–3 years
181
4–7 years
299
8–11 years
245
12+ years
65

About this medicine

Oclacitinib controls itching from allergies (tablet, a JAK inhibitor).

Products with this ingredient include Apoquel. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Oclacitinib cause swelling in dogs?
824 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 14 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Swelling with similar medicines

All reported side effects of Oclacitinib in dogs · Medicines most reported with swelling