Skin rash or irritation after Oclacitinib (Apoquel) in dogs

1,002 reports to the FDA describe skin rash or irritation in dogs given Oclacitinib. That is 3.5% of all reports for this medicine, compared with 1.3% across reports for all dog medicines, so it is reported unusually often with this medicine.

1,002Reports
32%Marked serious
7.3%Recovered
3.8%Died or euthanised
36 daysTypical onset
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How soon it started

Same day
79 11%
1–2 days
49 6.9%
3–7 days
42 5.9%
1–4 weeks
149 21%
Over a month
388 55%

How the animals did

Recovered
69 6.9%
Recovered with lasting effects
4 0.4%
Still unwell when reported
744 74%
Died
15 1.5%
Euthanised
23 2.3%
Not known
147 15%

Problems reported at the same time

Age of the animals

Under 1 year
10
1–3 years
190
4–7 years
354
8–11 years
318
12+ years
94

About this medicine

Oclacitinib controls itching from allergies (tablet, a JAK inhibitor).

Products with this ingredient include Apoquel. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Oclacitinib cause skin rash or irritation in dogs?
1,002 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 36 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Skin rash or irritation with similar medicines

All reported side effects of Oclacitinib in dogs · Medicines most reported with skin rash or irritation