Skin rash or irritation after Ilunocitinib (Zenrelia) in dogs

The FDA has received 100 reports of skin rash or irritation in dogs after Ilunocitinib. That is 4.5% of all reports for this medicine, compared with 1.3% across reports for all dog medicines, so it is reported unusually often with this medicine.

100Reports
27%Marked serious
10%Recovered
7.0%Died or euthanised
97 daysTypical onset
SponsoredWorried about your pet? Ask a veterinarian online, 24/7

How soon it started

Same day
3 3.4%
1–2 days
4 4.6%
3–7 days
3 3.4%
1–4 weeks
11 13%
Over a month
66 76%

How the animals did

Recovered
10 10%
Still unwell when reported
48 48%
Died
3 3.0%
Euthanised
4 4.0%
Not known
35 35%

Problems reported at the same time

Age of the animals

Under 1 year
1
1–3 years
21
4–7 years
42
8–11 years
27
12+ years
6

About this medicine

Ilunocitinib controls itching from allergies (tablet, a JAK inhibitor).

Products with this ingredient include Zenrelia. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Ilunocitinib cause skin rash or irritation in dogs?
100 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 97 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Skin rash or irritation with similar medicines

All reported side effects of Ilunocitinib in dogs · Medicines most reported with skin rash or irritation