Not himself/herself after Oclacitinib (Apoquel) in dogs

The FDA has received 144 reports of not himself/herself in dogs after Oclacitinib. That is 0.5% of all reports for this medicine, compared with 0.3% across reports for all dog medicines, so it is reported unusually often with this medicine.

144Reports

56%Marked serious

19%Recovered

15%Died or euthanised

10 daysTypical onset

How soon it started

Same day

35 29%

1–2 days

16 13%

3–7 days

9 7.5%

1–4 weeks

18 15%

Over a month

42 35%

How the animals did

Recovered

28 19%

Still unwell when reported

64 44%

Died

5 3.5%

Euthanised

17 12%

Not known

30 21%

Problems reported at the same time

63 44%

46 32%

41 28%

23 16%

22 15%

21 15%

20 14%

20 14%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Oclacitinib controls itching from allergies (tablet, a JAK inhibitor).

Products with this ingredient include Apoquel. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Oclacitinib cause not himself/herself in dogs?: 144 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 10 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Not himself/herself with similar medicines

Not himself/herself after Ilunocitinib (Zenrelia) 32 reports · 1.5% of its reports

All reported side effects of Oclacitinib in dogs · Medicines most reported with not himself/herself