Eye disorder (for photophobia see 'neurological') after Oclacitinib (Apoquel) in dogs

120 reports to the FDA describe eye disorder (for photophobia see 'neurological') in dogs given Oclacitinib. That is 0.4% of all reports for this medicine, compared with 0.2% across reports for all dog medicines, so it is reported unusually often with this medicine.

120Reports
49%Marked serious
19%Recovered
6.7%Died or euthanised
18 daysTypical onset
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How soon it started

Same day
18 21%
1–2 days
10 11%
3–7 days
6 6.9%
1–4 weeks
22 25%
Over a month
31 36%

How the animals did

Recovered
21 18%
Recovered with lasting effects
2 1.7%
Still unwell when reported
71 59%
Died
3 2.5%
Euthanised
5 4.2%
Not known
18 15%

Problems reported at the same time

Age of the animals

Under 1 year
2
1–3 years
10
4–7 years
43
8–11 years
41
12+ years
19

About this medicine

Oclacitinib controls itching from allergies (tablet, a JAK inhibitor).

Products with this ingredient include Apoquel. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Oclacitinib cause eye disorder (for photophobia see 'neurological') in dogs?
120 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 18 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Eye disorder (for photophobia see 'neurological') with similar medicines

All reported side effects of Oclacitinib in dogs · Medicines most reported with eye disorder (for photophobia see 'neurological')