Crust after Oclacitinib (Apoquel) in dogs

182 reports to the FDA describe crust in dogs given Oclacitinib. That is 0.6% of all reports for this medicine, compared with 0.2% across reports for all dog medicines, so it is reported unusually often with this medicine.

182Reports

41%Marked serious

4.4%Recovered

4.4%Died or euthanised

28 daysTypical onset

How soon it started

Same day

14 11%

1–2 days

7 5.6%

3–7 days

11 8.9%

1–4 weeks

32 26%

Over a month

60 48%

How the animals did

Recovered

8 4.4%

Still unwell when reported

149 82%

Died

1 0.5%

Euthanised

7 3.8%

Not known

17 9.3%

Problems reported at the same time

Skin rash or irritation

66 36%

Didn't work as expected

66 36%

59 32%

53 29%

39 21%

30 16%

Bacterial skin infection

27 15%

Loss of appetite

26 14%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Oclacitinib controls itching from allergies (tablet, a JAK inhibitor).

Products with this ingredient include Apoquel. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Oclacitinib cause crust in dogs?: 182 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 28 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Crust with similar medicines

Crust after Cyclosporine (Atopica) 111 reports · 0.7% of its reports

All reported side effects of Oclacitinib in dogs · Medicines most reported with crust