Crust after Cyclosporine (Atopica) in dogs

The FDA has received 111 reports of crust in dogs after Cyclosporine. That is 0.7% of all reports for this medicine, compared with 0.2% across reports for all dog medicines, so it is reported unusually often with this medicine.

111Reports

39%Marked serious

7.2%Recovered

8.1%Died or euthanised

23 daysTypical onset

How soon it started

Same day

8 17%

1–2 days

4 8.3%

3–7 days

1 2.1%

1–4 weeks

17 35%

Over a month

18 38%

How the animals did

Recovered

8 7.2%

Still unwell when reported

28 25%

Died

1 0.9%

Euthanised

8 7.2%

Not known

66 59%

Problems reported at the same time

Skin rash or irritation

47 42%

30 27%

27 24%

21 19%

20 18%

18 16%

18 16%

Didn't work as expected

16 14%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Cyclosporine controls allergic skin disease and some immune conditions.

Products with this ingredient include Atopica. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Cyclosporine cause crust in dogs?: 111 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 23 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Crust with similar medicines

Crust after Oclacitinib (Apoquel) 182 reports · 0.6% of its reports

All reported side effects of Cyclosporine in dogs · Medicines most reported with crust