Blood in vomit after Oclacitinib (Apoquel) in dogs

The FDA has received 94 reports of blood in vomit in dogs after Oclacitinib. That is 0.3% of all reports for this medicine, compared with 0.4% across reports for all dog medicines.

94Reports

51%Marked serious

20%Recovered

14%Died or euthanised

5 daysTypical onset

How soon it started

Same day

17 24%

1–2 days

13 18%

3–7 days

9 13%

1–4 weeks

15 21%

Over a month

18 25%

How the animals did

Recovered

19 20%

Still unwell when reported

46 49%

Died

4 4.3%

Euthanised

9 9.6%

Not known

16 17%

Problems reported at the same time

40 43%

34 36%

31 33%

31 33%

19 20%

14 15%

13 14%

10 11%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Oclacitinib controls itching from allergies (tablet, a JAK inhibitor).

Products with this ingredient include Apoquel. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Oclacitinib cause blood in vomit in dogs?: 94 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 5 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Blood in vomit with similar medicines

Blood in vomit after Cyclosporine (Atopica) 90 reports · 0.6% of its reports

All reported side effects of Oclacitinib in dogs · Medicines most reported with blood in vomit