Deafness after Neomycin + Nystatin Usp + Thiostrepton Usp + Triamcinolone in dogs

The FDA has received 59 reports of deafness in dogs after Neomycin + Nystatin Usp + Thiostrepton Usp + Triamcinolone. That is 38% of all reports for this medicine, compared with 0.6% across reports for all dog medicines, so it is reported unusually often with this medicine.

59Reports

59%Marked serious

19%Recovered

0.0%Died or euthanised

5 daysTypical onset

How soon it started

Same day

3 5.6%

1–2 days

13 24%

3–7 days

27 50%

1–4 weeks

8 15%

Over a month

3 5.6%

How the animals did

Recovered

10 17%

Recovered with lasting effects

1 1.7%

Still unwell when reported

41 69%

Not known

7 12%

Problems reported at the same time

Pr-ear(s), lesion(s)

14 24%

Nystagmus

1 1.7%

Neurological symptoms

1 1.7%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Type: medicine.

Questions owners ask

Can Neomycin + Nystatin Usp + Thiostrepton Usp + Triamcinolone cause deafness in dogs?: 59 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 5 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Deafness with similar medicines

Deafness after Cefpodoxime 49 reports · 1.2% of its reports
Deafness after Florfenicol + Mometasone + Terbinafine 225 reports · 6.4% of its reports
Deafness after Isoflurane 21 reports · 0.8% of its reports
Deafness after Cephalexin 22 reports · 0.8% of its reports
Deafness after Clotrimazole + Gentamicin + Mometasone 804 reports · 31% of its reports
Deafness after Betamethasone + Florfenicol + Terbinafine 182 reports · 7.4% of its reports
Deafness after Genta Momet Clotrim 1,446 reports · 63% of its reports
Deafness after Ketoconazole 87 reports · 3.9% of its reports
Deafness after Betamethasone + Clotrimazole + Gentamicin 1,165 reports · 59% of its reports
Deafness after Neomycin + Triamcinolone 126 reports · 27% of its reports

All reported side effects of Neomycin + Nystatin Usp + Thiostrepton Usp + Triamcinolone in dogs · Medicines most reported with deafness