Deafness after Neomycin + Nystatin + Thiostrepton in dogs

The FDA has received 33 reports of deafness in dogs after Neomycin + Nystatin + Thiostrepton. That is 66% of all reports for this medicine, compared with 0.6% across reports for all dog medicines, so it is reported unusually often with this medicine.

33Reports
100%Marked serious
27%Recovered
0.0%Died or euthanised
–Typical onset
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How the animals did

Recovered
3 9.1%
Recovered with lasting effects
6 18%
Still unwell when reported
2 6.1%
Not known
22 67%

Problems reported at the same time

Ear canal disorder
3 9.1%
Partial deafness
3 9.1%
Otorrhoea
2 6.1%
Impaired hearing
1 3.0%
Vomiting
1 3.0%
Didn't work as expected
1 3.0%
Application site reaction
1 3.0%
Allergic reaction
1 3.0%

Age of the animals

Under 1 year
0
1–3 years
0
4–7 years
2
8–11 years
13
12+ years
14

About this medicine

Type: medicine.

Questions owners ask

Can Neomycin + Nystatin + Thiostrepton cause deafness in dogs?
33 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Deafness with similar medicines

All reported side effects of Neomycin + Nystatin + Thiostrepton in dogs · Medicines most reported with deafness