Swelling after Miconazole + Polymyxin B + Prednisolone in dogs

34 reports to the FDA describe swelling in dogs given Miconazole + Polymyxin B + Prednisolone. That is 3.1% of all reports for this medicine, compared with 2.8% across reports for all dog medicines.

34Reports
35%Marked serious
38%Recovered
0.0%Died or euthanised
1 daysTypical onset
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How soon it started

Same day
11 46%
1–2 days
4 17%
3–7 days
3 13%
1–4 weeks
3 13%
Over a month
3 13%

How the animals did

Recovered
11 32%
Recovered with lasting effects
2 5.9%
Still unwell when reported
9 26%
Not known
12 35%

Problems reported at the same time

Age of the animals

Under 1 year
3
1–3 years
10
4–7 years
9
8–11 years
8
12+ years
2

About this medicine

Prednisolone reduces inflammation and immune activity.

Steroids commonly cause increased thirst, urination and appetite, especially at higher doses.

Questions owners ask

Can Miconazole + Polymyxin B + Prednisolone cause swelling in dogs?
34 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 1 day of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Swelling with similar medicines

All reported side effects of Miconazole + Polymyxin B + Prednisolone in dogs · Medicines most reported with swelling