Deafness after Miconazole + Polymyxin B + Prednisolone in dogs
The FDA has received 283 reports of deafness in dogs after Miconazole + Polymyxin B + Prednisolone. That is 26% of all reports for this medicine, compared with 0.6% across reports for all dog medicines, so it is reported unusually often with this medicine.
283Reports
80%Marked serious
29%Recovered
0.4%Died or euthanised
5 daysTypical onset
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How soon it started
How the animals did
Problems reported at the same time
Age of the animals
About this medicine
Prednisolone reduces inflammation and immune activity.
Steroids commonly cause increased thirst, urination and appetite, especially at higher doses.
Questions owners ask
- Can Miconazole + Polymyxin B + Prednisolone cause deafness in dogs?
- 283 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
- How soon after a dose was it reported?
- In half of the reports with dates, it started within 5 days of the first dose.
- What should I do?
- Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).
Deafness with similar medicines
- Deafness after Prednisone 57 reports · 0.6% of its reports
- Deafness after Dexamethasone 24 reports · 0.9% of its reports
- Deafness after Dexamethasone + Neomycin + Thiabendazole 84 reports · 13% of its reports
All reported side effects of Miconazole + Polymyxin B + Prednisolone in dogs · Medicines most reported with deafness