Seizures after Methylprednisolone in dogs

The FDA has received 29 reports of seizures in dogs after Methylprednisolone. That is 4.3% of all reports for this medicine, compared with 4.4% across reports for all dog medicines.

29Reports
59%Marked serious
14%Recovered
21%Died or euthanised
5 daysTypical onset
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How soon it started

Same day
5 31%
1–2 days
2 13%
3–7 days
2 13%
1–4 weeks
1 6.3%
Over a month
6 38%

How the animals did

Recovered
4 14%
Still unwell when reported
9 31%
Died
5 17%
Euthanised
1 3.4%
Not known
10 34%

Problems reported at the same time

6 21%
Drooling
5 17%
Disorientation
4 14%
Vocalising
4 14%
Lateral recumbency
4 14%

Age of the animals

Under 1 year
0
1–3 years
8
4–7 years
6
8–11 years
12
12+ years
3

About this medicine

Type: medicine.

Questions owners ask

Can Methylprednisolone cause seizures in dogs?
29 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 5 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Seizures with similar medicines

All reported side effects of Methylprednisolone in dogs · Medicines most reported with seizures