Pacing after Melarsomine (Immiticide) in dogs

The FDA has received 138 reports of pacing in dogs after Melarsomine. That is 0.6% of all reports for this medicine, compared with 0.3% across reports for all dog medicines, so it is reported unusually often with this medicine.

138Reports

35%Marked serious

17%Recovered

2.2%Died or euthanised

Same dayTypical onset

How soon it started

Same day

60 73%

1–2 days

4 4.9%

3–7 days

2 2.4%

1–4 weeks

9 11%

Over a month

7 8.5%

How the animals did

Recovered

23 17%

Still unwell when reported

36 26%

Died

2 1.4%

Euthanised

1 0.7%

Not known

76 55%

Problems reported at the same time

52 38%

38 28%

36 26%

36 26%

35 25%

Restlessness or agitation

28 20%

Vomiting

21 15%

Injection site reaction

17 12%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Melarsomine treats adult heartworm infection (a series of injections given by a vet).

Products with this ingredient include Immiticide, Diroban. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Melarsomine cause pacing in dogs?: 138 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within the same day of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Pacing with similar medicines

Pacing after Polysulfated Glycosaminoglycan 35 reports · 0.6% of its reports
Pacing after Diphenhydramine 31 reports · 0.7% of its reports
Pacing after Butorphanol 32 reports · 0.7% of its reports
Pacing after Cefpodoxime 27 reports · 0.7% of its reports
Pacing after Tramadol 40 reports · 1.1% of its reports
Pacing after Florfenicol + Mometasone + Terbinafine 24 reports · 0.7% of its reports
Pacing after Atipamezole 23 reports · 0.9% of its reports
Pacing after Famotidine 20 reports · 0.8% of its reports
Pacing after Chondroitin + Glucosamine 24 reports · 0.9% of its reports

All reported side effects of Melarsomine in dogs · Medicines most reported with pacing