Muscle stiffness after Melarsomine (Immiticide) in dogs

41 reports to the FDA describe muscle stiffness in dogs given Melarsomine. That is 0.2% of all reports for this medicine, compared with 0.1% across reports for all dog medicines, so it is reported unusually often with this medicine.

41Reports

9.8%Marked serious

4.9%Recovered

15%Died or euthanised

–Typical onset

How the animals did

Recovered

2 4.9%

Still unwell when reported

1 2.4%

Died

6 15%

Not known

32 78%

Problems reported at the same time

Fever

13 32%

Loss of appetite

11 27%

Vomiting

11 27%

Injection site reaction

10 24%

10 24%

9 22%

6 15%

5 12%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Melarsomine treats adult heartworm infection (a series of injections given by a vet).

Products with this ingredient include Immiticide, Diroban. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Melarsomine cause muscle stiffness in dogs?: 41 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

All reported side effects of Melarsomine in dogs · Medicines most reported with muscle stiffness