Hind limb paralysis after Melarsomine (Immiticide) in dogs

151 reports to the FDA describe hind limb paralysis in dogs given Melarsomine. That is 0.7% of all reports for this medicine, compared with 0.1% across reports for all dog medicines, so it is reported unusually often with this medicine.

151Reports
44%Marked serious
2.0%Recovered
25%Died or euthanised
1 daysTypical onset
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How soon it started

Same day
22 34%
1–2 days
20 31%
3–7 days
5 7.8%
1–4 weeks
8 13%
Over a month
9 14%

How the animals did

Recovered
2 1.3%
Recovered with lasting effects
1 0.7%
Still unwell when reported
35 23%
Died
31 21%
Euthanised
7 4.6%
Not known
75 50%

Problems reported at the same time

Age of the animals

Under 1 year
3
1–3 years
69
4–7 years
48
8–11 years
18
12+ years
5

About this medicine

Melarsomine treats adult heartworm infection (a series of injections given by a vet).

Products with this ingredient include Immiticide, Diroban. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Melarsomine cause hind limb paralysis in dogs?
151 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 1 day of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Hind limb paralysis with similar medicines

All reported side effects of Melarsomine in dogs · Medicines most reported with hind limb paralysis