Hind limb paresis after Melarsomine (Immiticide) in dogs

267 reports to the FDA describe hind limb paresis in dogs given Melarsomine. That is 1.2% of all reports for this medicine, compared with 0.3% across reports for all dog medicines, so it is reported unusually often with this medicine.

267Reports

24%Marked serious

3.4%Recovered

13%Died or euthanised

1 daysTypical onset

How soon it started

Same day

23 36%

1–2 days

13 20%

3–7 days

1 1.6%

1–4 weeks

14 22%

Over a month

13 20%

How the animals did

Recovered

5 1.9%

Recovered with lasting effects

4 1.5%

Still unwell when reported

25 9.4%

Died

30 11%

Euthanised

4 1.5%

Not known

199 75%

Problems reported at the same time

Pain

57 21%

Injection site reaction

55 21%

Wobbliness (ataxia)

50 19%

Loss of appetite

39 15%

Proprioception abnormality

37 14%

Death

34 13%

Swelling

34 13%

Lethargy

30 11%

Age of the animals

Under 1 year

1–3 years

110

4–7 years

8–11 years

12+ years

About this medicine

Melarsomine treats adult heartworm infection (a series of injections given by a vet).

Products with this ingredient include Immiticide, Diroban. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Melarsomine cause hind limb paresis in dogs?: 267 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 1 day of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Hind limb paresis with similar medicines

Hind limb paresis after Polysulfated Glycosaminoglycan 45 reports · 0.8% of its reports
Hind limb paresis after Cefpodoxime 20 reports · 0.5% of its reports
Hind limb paresis after Tramadol 34 reports · 0.9% of its reports
Hind limb paresis after Desoxycorticosterone Pivalate 21 reports · 0.6% of its reports
Hind limb paresis after Chondroitin + Glucosamine 26 reports · 1.0% of its reports
Hind limb paresis after Methocarbamol 20 reports · 3.2% of its reports
Hind limb paresis after Amantadine 26 reports · 5.1% of its reports

All reported side effects of Melarsomine in dogs · Medicines most reported with hind limb paresis