Apnoea after Melarsomine (Immiticide) in dogs

The FDA has received 25 reports of apnoea in dogs after Melarsomine. That is 0.1% of all reports for this medicine, compared with 0.2% across reports for all dog medicines.

25Reports
28%Marked serious
8.0%Recovered
76%Died or euthanised
–Typical onset
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How the animals did

Recovered
2 8.0%
Still unwell when reported
1 4.0%
Died
18 72%
Euthanised
1 4.0%
Not known
3 12%

Problems reported at the same time

Age of the animals

Under 1 year
0
1–3 years
10
4–7 years
11
8–11 years
2
12+ years
1

About this medicine

Melarsomine treats adult heartworm infection (a series of injections given by a vet).

Products with this ingredient include Immiticide, Diroban. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Melarsomine cause apnoea in dogs?
25 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Apnoea with similar medicines

All reported side effects of Melarsomine in dogs · Medicines most reported with apnoea