Unresponsive after Lokivetmab (Cytopoint) in dogs

59 reports to the FDA describe unresponsive in dogs given Lokivetmab. That is 0.9% of all reports for this medicine, compared with 0.4% across reports for all dog medicines, so it is reported unusually often with this medicine.

59Reports

98%Marked serious

10%Recovered

34%Died or euthanised

15 daysTypical onset

How soon it started

Same day

8 21%

1–2 days

6 16%

3–7 days

3 7.9%

1–4 weeks

8 21%

Over a month

13 34%

How the animals did

Recovered

6 10%

Still unwell when reported

27 46%

Died

11 19%

Euthanised

9 15%

Not known

6 10%

Problems reported at the same time

20 34%

15 25%

12 20%

12 20%

9 15%

8 14%

Didn't work as expected

8 14%

Diarrhea

7 12%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Lokivetmab controls allergic itch for 4–8 weeks per injection.

Products with this ingredient include Cytopoint. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Lokivetmab cause unresponsive in dogs?: 59 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 15 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Unresponsive with similar medicines

Unresponsive after Bedinvetmab (Librela) 208 reports · 1.1% of its reports

All reported side effects of Lokivetmab in dogs · Medicines most reported with unresponsive