Loose stool after Lokivetmab (Cytopoint) in dogs

The FDA has received 90 reports of loose stool in dogs after Lokivetmab. That is 1.4% of all reports for this medicine, compared with 0.9% across reports for all dog medicines, so it is reported unusually often with this medicine.

90Reports
47%Marked serious
11%Recovered
10%Died or euthanised
6 daysTypical onset
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How soon it started

Same day
19 26%
1–2 days
11 15%
3–7 days
10 14%
1–4 weeks
12 17%
Over a month
20 28%

How the animals did

Recovered
10 11%
Still unwell when reported
60 67%
Died
3 3.3%
Euthanised
6 6.7%
Not known
11 12%

Problems reported at the same time

Vomiting
54 60%
Lethargy
40 44%
Loss of appetite
38 42%
Didn't work as expected
20 22%
Diarrhea
19 21%
Liver problems
14 16%
Kidney problems
11 12%
Blood problems
11 12%

Age of the animals

Under 1 year
0
1–3 years
17
4–7 years
28
8–11 years
33
12+ years
10

About this medicine

Lokivetmab controls allergic itch for 4–8 weeks per injection.

Products with this ingredient include Cytopoint. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Lokivetmab cause loose stool in dogs?
90 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 6 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Loose stool with similar medicines

All reported side effects of Lokivetmab in dogs · Medicines most reported with loose stool