Increased red blood cell count after Leptospirosis Vaccine in dogs

21 reports to the FDA describe increased red blood cell count in dogs given Leptospirosis Vaccine. That is 0.3% of all reports for this medicine, compared with 0.0% across reports for all dog medicines, so it is reported unusually often with this medicine.

21Reports

86%Marked serious

14%Recovered

24%Died or euthanised

1 daysTypical onset

How soon it started

Same day

9 50%

1–2 days

1 5.6%

3–7 days

2 11%

1–4 weeks

2 11%

Over a month

4 22%

How the animals did

Recovered

3 14%

Still unwell when reported

8 38%

Died

1 4.8%

Euthanised

4 19%

Not known

5 24%

Problems reported at the same time

13 62%

12 57%

11 52%

9 43%

7 33%

6 29%

5 24%

Hemoglobin(hb) high, blood

5 24%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Type: vaccine.

Mild, short-lived lethargy, soreness or a small lump at the injection site are the most commonly reported vaccine reactions.

Questions owners ask

Can Leptospirosis Vaccine cause increased red blood cell count in dogs?: 21 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 1 day of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

All reported side effects of Leptospirosis Vaccine in dogs · Medicines most reported with increased red blood cell count