Decreased haematocrit after Leptospirosis Vaccine in dogs

57 reports to the FDA describe decreased haematocrit in dogs given Leptospirosis Vaccine. That is 0.7% of all reports for this medicine, compared with 0.1% across reports for all dog medicines, so it is reported unusually often with this medicine.

57Reports
86%Marked serious
7.0%Recovered
28%Died or euthanised
21 daysTypical onset
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How soon it started

Same day
5 10%
1–2 days
5 10%
3–7 days
5 10%
1–4 weeks
15 31%
Over a month
18 38%

How the animals did

Recovered
4 7.0%
Still unwell when reported
25 44%
Died
4 7.0%
Euthanised
12 21%
Not known
12 21%

Problems reported at the same time

Age of the animals

Under 1 year
13
1–3 years
14
4–7 years
16
8–11 years
7
12+ years
4

About this medicine

Type: vaccine.

Mild, short-lived lethargy, soreness or a small lump at the injection site are the most commonly reported vaccine reactions.

Questions owners ask

Can Leptospirosis Vaccine cause decreased haematocrit in dogs?
57 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 21 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Decreased haematocrit with similar medicines

All reported side effects of Leptospirosis Vaccine in dogs · Medicines most reported with decreased haematocrit