Lymphopenia after Ketoconazole in dogs

48 reports to the FDA describe lymphopenia in dogs given Ketoconazole. That is 2.1% of all reports for this medicine, compared with 0.3% across reports for all dog medicines, so it is reported unusually often with this medicine.

48Reports
56%Marked serious
15%Recovered
17%Died or euthanised
33 daysTypical onset
SponsoredWorried about your pet? Ask a veterinarian online, 24/7

How soon it started

Same day
3 7.3%
1–2 days
3 7.3%
3–7 days
1 2.4%
1–4 weeks
11 27%
Over a month
23 56%

How the animals did

Recovered
7 15%
Still unwell when reported
24 50%
Died
5 10%
Euthanised
3 6.3%
Not known
9 19%

Problems reported at the same time

Age of the animals

Under 1 year
0
1–3 years
10
4–7 years
24
8–11 years
10
12+ years
4

About this medicine

Type: medicine.

Questions owners ask

Can Ketoconazole cause lymphopenia in dogs?
48 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 33 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Lymphopenia with similar medicines

All reported side effects of Ketoconazole in dogs · Medicines most reported with lymphopenia