Loss of hearing after Ketoconazole in dogs

98 reports to the FDA describe loss of hearing in dogs given Ketoconazole. That is 4.3% of all reports for this medicine, compared with 0.2% across reports for all dog medicines, so it is reported unusually often with this medicine.

98Reports

100%Marked serious

26%Recovered

0.0%Died or euthanised

4 daysTypical onset

How soon it started

Same day

9 10%

1–2 days

25 28%

3–7 days

23 26%

1–4 weeks

16 18%

Over a month

16 18%

How the animals did

Recovered

11 11%

Recovered with lasting effects

14 14%

Still unwell when reported

36 37%

Not known

37 38%

Problems reported at the same time

10 10%

10 10%

8 8.2%

7 7.1%

Didn't work as expected

7 7.1%

Lethargy

6 6.1%

Weight loss

5 5.1%

Abnormal cytology

5 5.1%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Type: medicine.

Questions owners ask

Can Ketoconazole cause loss of hearing in dogs?: 98 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 4 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Loss of hearing with similar medicines

Loss of hearing after Cefpodoxime 30 reports · 0.7% of its reports
Loss of hearing after Florfenicol + Mometasone + Terbinafine 113 reports · 3.2% of its reports
Loss of hearing after Clotrimazole + Gentamicin + Mometasone 308 reports · 12% of its reports
Loss of hearing after Betamethasone + Florfenicol + Terbinafine 152 reports · 6.2% of its reports
Loss of hearing after Genta Momet Clotrim 95 reports · 4.1% of its reports
Loss of hearing after Betamethasone + Clotrimazole + Gentamicin 22 reports · 1.1% of its reports
Loss of hearing after Gentamicin + Hydrocortisone Aceponate + Miconazole 263 reports · 57% of its reports
Loss of hearing after Gentamicin + Miconazole 40 reports · 11% of its reports
Loss of hearing after Neomycin + Nystatin + Thiostrepton + Triamcinolone 61 reports · 24% of its reports
Loss of hearing after Salicylic Acid 35 reports · 20% of its reports

All reported side effects of Ketoconazole in dogs · Medicines most reported with loss of hearing