Loss of hearing after Betamethasone + Florfenicol + Terbinafine in dogs

152 reports to the FDA describe loss of hearing in dogs given Betamethasone + Florfenicol + Terbinafine. That is 6.2% of all reports for this medicine, compared with 0.2% across reports for all dog medicines, so it is reported unusually often with this medicine.

152Reports

99%Marked serious

41%Recovered

0.7%Died or euthanised

4 daysTypical onset

How soon it started

Same day

22 16%

1–2 days

38 27%

3–7 days

17 12%

1–4 weeks

33 24%

Over a month

29 21%

How the animals did

Recovered

44 29%

Recovered with lasting effects

18 12%

Still unwell when reported

32 21%

Euthanised

1 0.7%

Not known

57 38%

Problems reported at the same time

Didn't work as expected

14 9.2%

13 8.6%

12 7.9%

8 5.3%

6 3.9%

6 3.9%

Anxiety

5 3.3%

Vocalising

5 3.3%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Type: medicine.

Questions owners ask

Can Betamethasone + Florfenicol + Terbinafine cause loss of hearing in dogs?: 152 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 4 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Loss of hearing with similar medicines

Loss of hearing after Cefpodoxime 30 reports · 0.7% of its reports
Loss of hearing after Florfenicol + Mometasone + Terbinafine 113 reports · 3.2% of its reports
Loss of hearing after Clotrimazole + Gentamicin + Mometasone 308 reports · 12% of its reports
Loss of hearing after Genta Momet Clotrim 95 reports · 4.1% of its reports
Loss of hearing after Ketoconazole 98 reports · 4.3% of its reports
Loss of hearing after Betamethasone + Clotrimazole + Gentamicin 22 reports · 1.1% of its reports
Loss of hearing after Gentamicin + Hydrocortisone Aceponate + Miconazole 263 reports · 57% of its reports
Loss of hearing after Gentamicin + Miconazole 40 reports · 11% of its reports
Loss of hearing after Neomycin + Nystatin + Thiostrepton + Triamcinolone 61 reports · 24% of its reports
Loss of hearing after Salicylic Acid 35 reports · 20% of its reports

All reported side effects of Betamethasone + Florfenicol + Terbinafine in dogs · Medicines most reported with loss of hearing