Loss of hearing after Clotrimazole + Gentamicin + Mometasone in dogs

308 reports to the FDA describe loss of hearing in dogs given Clotrimazole + Gentamicin + Mometasone. That is 12% of all reports for this medicine, compared with 0.2% across reports for all dog medicines, so it is reported unusually often with this medicine.

308Reports

26%Marked serious

23%Recovered

1.0%Died or euthanised

7 daysTypical onset

How soon it started

Same day

2 2.4%

1–2 days

16 20%

3–7 days

27 33%

1–4 weeks

18 22%

Over a month

19 23%

How the animals did

Recovered

27 8.8%

Recovered with lasting effects

45 15%

Still unwell when reported

149 48%

Died

1 0.3%

Euthanised

2 0.6%

Not known

84 27%

Problems reported at the same time

Loss of appetite

6 1.9%

Application site reaction

5 1.6%

Drug administration duration too long

4 1.3%

Impaired hearing

3 1.0%

Death

3 1.0%

Partial deafness

3 1.0%

Tympanic rupture

3 1.0%

Lethargy

3 1.0%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

115

12+ years

111

About this medicine

Type: medicine.

Questions owners ask

Can Clotrimazole + Gentamicin + Mometasone cause loss of hearing in dogs?: 308 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 7 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Loss of hearing with similar medicines

Loss of hearing after Cefpodoxime 30 reports · 0.7% of its reports
Loss of hearing after Florfenicol + Mometasone + Terbinafine 113 reports · 3.2% of its reports
Loss of hearing after Betamethasone + Florfenicol + Terbinafine 152 reports · 6.2% of its reports
Loss of hearing after Genta Momet Clotrim 95 reports · 4.1% of its reports
Loss of hearing after Ketoconazole 98 reports · 4.3% of its reports
Loss of hearing after Betamethasone + Clotrimazole + Gentamicin 22 reports · 1.1% of its reports
Loss of hearing after Gentamicin + Hydrocortisone Aceponate + Miconazole 263 reports · 57% of its reports
Loss of hearing after Gentamicin + Miconazole 40 reports · 11% of its reports
Loss of hearing after Neomycin + Nystatin + Thiostrepton + Triamcinolone 61 reports · 24% of its reports
Loss of hearing after Salicylic Acid 35 reports · 20% of its reports

All reported side effects of Clotrimazole + Gentamicin + Mometasone in dogs · Medicines most reported with loss of hearing